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The document discusses the continuous flow C-glycosylation process via metal-halogen exchange, focusing on the synthesis and analysis of starting materials for the efficient manufacturing of Remdesivir. It details various experimental methods, including calorimetric analysis and batch experiments, to understand the reactions and optimize the process. The findings include insights on solubility, reaction conditions, and the formation of side products during the synthesis.
- Author
- arun manchekar
- Language
- EN