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Prevalence and predictors of suboptimal peak inspiratory flow rate in COPD patients by Harb, Hadeer S.; Laz, Nabila Ibrahim; Rabea, Hoda; Abdelrahim, Mohamed E.A. is a Pharmacology, Toxicology and Pharmaceutics article available to read on EtoBox.

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The aim of this study was to determine prevalence and possible clinical predictors of suboptimal peak inspiratory flow rate (PIFR) with different dry powder inhalers. PIFR was measured across all resistance ranges of In-Check Dial® in 180 chronic obstructive pulmonary disease (COPD) subjects before hospital discharge. COPD subjects were defined as suboptimal if measured PIFR was suboptimal with any resistance representative of specific inhalers (R1-R5). Demographics and clinical data were collected, including COPD Assessment Test (CAT) and modified Medical Research Council (mMRC) scores, Global Initiative for Obstructive Lung Disease (GOLD) stage spirometry by Spirodoc® and peak flow meter measurements with portable peak inspiratory and expiratory flow meters. All were correlated with In-Check Dial PIFRs. Suboptimal PIFR was 44.44% prevalent in COPD subjects. 55% of the suboptimal cohort was female which represent 57.14% of the total female population in the study. The distribution of suboptimal PIFR included 43.75% with R1, 67.5% with R2, 100% with R3, 13.75% with R4, and 21.25% with R5. In the suboptimal cohort, CAT score was significantly higher and spirometry demonstrated signi

Who reads Prevalence and predictors of suboptimal peak inspiratory flow rate in COPD patients?

Author

Harb, Hadeer S.; Laz, Nabila Ibrahim; Rabea, Hoda; Abdelrahim, Mohamed E.A.

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0928-0987)

Published

2020

Language

EN

Field

Pharmacology, Toxicology and Pharmaceutics (Life Sciences)