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Decoding the Genetic Code Breakthrough by knorbert6 is a document available to read on EtoBox.
Scientists in the 1960s used synthetic RNA molecules and random nucleotide copolymers to decipher the genetic code by correlating the nucleotide sequences of these artificial mRNAs with the amino acid sequences of the resulting polypeptides. A major breakthrough was made by Nirenberg and Matthaei who showed that polyuridylic acid directed the synthesis of polyphenylalanine, assigning UUU as the codon for phenylalanine. Further experiments with random copolymers and defined repeating sequences by Nirenberg,
- Author
- knorbert6
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- EN