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Assessment of Quality of Life in Adults Receiving Long-term Growth Hormone Replacement Compared to Control Subjects by I. A. Malik; P. Foy; M. Wallymahmed; J. P. H. Wilding; I. A. MacFarlane is a Medicine article available to read on EtoBox.

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## Summary **objective** There are few studies of quality of life (QOL) in adults with growth hormone deficiency (GHD) compared to matched control populations without GHD. These have shown impairments in a variety of QOL measures, which improve but do not normalize after short‐term replacement with GH. There is little information on QOL in long‐term treated GHD patients compared with controls without GHD. **patients and methods** A total of 120 adults with GHD who had received GH replacement for at least 1 year were identified from the neuroendocrine clinic. Patients were asked to complete eight QOL questionnaires and an Energy Visual Analogue Scale (VAS). Results were compared with 83 control subjects without GHD from the local population who agreed to complete seven of the QOL questionnaires (excluding Disease Impact scale) and the energy VAS. The eight questionnaires were a combination of generic and disease‐specific questionnaires used to assess health related QOL, namely: Short Form‐36 (SF‐36), Nottingham Health Profile (NHP), Disease Impact, Life Fulfilment and Satisfaction scales, Mental Fatigue Questionnaire (MFQ) and Self Esteem scale, Hospital Anxiety Depression (HAD) sca

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Author

I. A. Malik; P. Foy; M. Wallymahmed; J. P. H. Wilding; I. A. MacFarlane

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley; Research Square (ISSN 0300-0664)

Published

2003

Language

EN

Field

Medicine (Health Sciences)