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Effects of Immunonutrition on Chemoradiotherapy Patients: A Systematic Review and Meta‐Analysis by Xiaoya Zheng; Kaili Yu; Guiyue Wang; Miao Liu; Yuhang Li; Pulin Yu; Mengyuan Yang; Nana Guo; Xiaohui Ma; Yue Bu; Yahui Peng; Ci Han; Kaijiang Yu; Changsong Wang is a Medicine article available to read on EtoBox.
What is Effects of Immunonutrition on Chemoradiotherapy Patients: A Systematic Review and Meta‐Analysis about?
## Objective: We conducted a systematic review to assess the effects of immunonutrition on chemoradiotherapy patients. ## Methods: We searched the cochrane central register of controlled trials, embase, medline, cinahl, and the web of science. we assessed the risk of bias using the cochrane risk of bias tool. our primary outcomes were the incidence of oral mucositis and diarrhea. the secondary outcomes were the incidence of esophagitis, grade ≥3 oral mucositis, grade ≥3 diarrhea, grade ≥3 esophagitis, and body weight loss. ## Results: A total of 1478 patients and 27 studies were included. there were no significant differences in the incidence of oral mucositis (relative risk [rr] = 0.91; 95% confidence interval [ci], 0.79-1.05), diarrhea (rr = 0.89; 95% ci, 0.76-1.05), or esophagitis (rr = 0.55; 95% ci, 0.11-2.86) between the immunonutrition group and standard nutrition/placebo group. nevertheless, immunonutrition significantly reduced the incidence of grade ≥3 oral mucositis (rr = 0.45; 95% ci, 0.22-0.92), grade ≥3 diarrhea (rr = 0.56; 95% ci, 0.35-0.88), grade ≥3 esophagitis (rr = 0.15; 95% ci, 0.04-0.54), and losing >5% body weight (rr = 0.34; 95% ci, 0.18-0.64). ## Conclusions:
Who reads Effects of Immunonutrition on Chemoradiotherapy Patients: A Systematic Review and Meta‐Analysis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Xiaoya Zheng; Kaili Yu; Guiyue Wang; Miao Liu; Yuhang Li; Pulin Yu; Mengyuan Yang; Nana Guo; Xiaohui Ma; Yue Bu; Yahui Peng; Ci Han; Kaijiang Yu; Changsong Wang
- Published
- 2019
- Language
- EN
- Field
- Medicine (Health Sciences)