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This study explores the use of poly(ethylene glycol)-b-poly(epsilon-caprolactone) nanoparticles for the oral delivery of cannabidiol (CBD), which faces challenges due to poor solubility and low bioavailability. The nanoparticles demonstrated high encapsulation efficiency and a significant increase in plasma concentration and absorption speed compared to free CBD, indicating improved oral bioavailability. These findings suggest that this nanotechnology platform could enhance the therapeutic use of CBD while

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gustavotorres.ufpr

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EN