Can I read Overview of the 2022 WHO Classification of Pituitary Tumors on EtoBox?
Overview of the 2022 WHO Classification of Pituitary Tumors by Sylvia L. Asa; Ozgur Mete; Arie Perry; Robert Y. Osamura is a Medicine article available to read on EtoBox.
What is Overview of the 2022 WHO Classification of Pituitary Tumors about?
This review summarizes the changes in the 5th Edition of the WHO Classification of Endocrine and Neuroendocrine Tumors that relate to the pituitary gland. The new classification clearly distinguishes anterior lobe (adenohypophyseal) from posterior lobe (neurohypophyseal) and hypothalamic tumors. Other tumors arising in the sellar region are also discussed. Anterior lobe tumors include (i) well-differentiated adenohypophyseal tumors that are now classified as pituitary neuroendocrine tumors (PitNETs; formerly known as pituitary adenomas), (ii) pituitary blastoma, and (iii) the two types of craniopharyngioma. The new WHO classification provides detailed histological subtyping of a PitNET based on the tumor cell lineage, cell type, and related characteristics. The routine use of immunohistochemistry for pituitary transcription factors (PIT1, TPIT, SF1, GATA3, and ERα) is endorsed in this classification. The major PIT1, TPIT, and SF1 lineage-defined PitNET types and subtypes feature distinct morphologic, molecular, and clinical differences. The "null cell" tumor, which is a diagnosis of exclusion, is reserved for PitNETs with no evidence of adenohypophyseal lineage differentiation. Unl
Who reads Overview of the 2022 WHO Classification of Pituitary Tumors?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Sylvia L. Asa; Ozgur Mete; Arie Perry; Robert Y. Osamura
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)