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What is Hepatic SAMe as Fasting Metabolic Sensor about?
The study by Capelo-Diz et al. reveals that hepatic S-adenosylmethionine (SAMe) serves as a metabolic sensor during fasting, regulating cellular responses by modulating lipid metabolism and ATP production in the liver. SAMe levels decrease during fasting, which helps prevent liver damage by controlling excessive mitochondrial activity and endoplasmic reticulum stress. The findings highlight the role of SAMe in the adaptive metabolic response to fasting, suggesting its potential as a target for metabolic hea
- Author
- mahabubalam
- Language
- EN