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Human Papillomavirus-Associated Head and Neck Cancers. Where are We Now? A Systematic Review by Miłosz Pinkiewicz; Karolina Dorobisz; Tomasz Zatoński is a Medicine article available to read on EtoBox.

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## Background Human papillomavirus targets the skin and mucous membranes, producing benign hyperplastic lesions and precancerous and cancerous lesions. An increasing number of head and neck cancersin particular, oropharyngeal squamous cell carcinoma, laryngeal squamous cell carcinoma, and oral squamous cell carcinoma, are attributable to HPV infection. HPV-induced HNCs typically affect younger, nonsmoking patients with no prior history of heavy alcohol use, more extensive sexual history, and higher socioeconomic status. ## Aim The purpose of the review is to present the most recent and well-established findings concerning HPV-induced head and neck cancers and consequently to provide medical specialists with essential information regarding the epidemiology, the role of HPV in HNC cancerogenesis, prevention, diagnosis, and treatment. ## Material and Methods All authors independently have searched The EMbase, Medline/Pubmed, and Cochrane databases by using the following keywords “head and neck cancer”, “human papillomavirus”, “HPV”, “HPV biology”, “oropharyngeal squamous cell carcinoma”, “carcinogenesis”, “transoral surgery”, “robotic surgery”. The last search was conducted in March 2

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Author

Miłosz Pinkiewicz; Karolina Dorobisz; Tomasz Zatoński

Publisher

Informa UK Limited

Published

2022

Language

EN

Field

Medicine (Health Sciences)