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Can I read Nutraceutical Resources for Diabetes Prevention – an Update on EtoBox?
Nutraceutical Resources for Diabetes Prevention – an Update by Mark F. McCarty is a Medicine article available to read on EtoBox.
What is Nutraceutical Resources for Diabetes Prevention – an Update about?
There is considerable need for safe agents that can reduce risk for diabetes in at-risk subjects. Although certain drugs – including metformin, acarbose, and orlistat – have shown diabetes-preventive activity in large randomized studies, nutraceuticals have potential in this regard as well. Natural agents which slow carbohydrate absorption may mimic the protective effect of acarbose; these include: soluble fiber – most notably glucomannan; chlorogenic acid – likely responsible for reduction in diabetes risk associated with heavy coffee intake; and legume-derived α-amylase inhibitors. There does not appear to be a natural lipase inhibitor functionally equivalent to orlistat, although there are poorly documented claims for Cassia nomame extracts. Metformin's efficacy reflects activation of AMP-activated kinase; there is preliminary evidence that certain compounds in barley malt have similar activity, without the side effects associated with metformin. In supraphysiological concentrations, biotin directly activates soluble guanylate cyclase; this implies that, at some sufficient intake, biotin should exert effects on β cells, the liver, and skeletal muscle that favor good glucose tole
Who reads Nutraceutical Resources for Diabetes Prevention – an Update?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Mark F. McCarty
- Publisher
- Elsevier BV
- Published
- 2005
- Language
- EN
- Field
- Medicine (Life Sciences)