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Navigated Transcranial Magnetic Stimulation Mapping of the Motor Cortex for Preoperative Diagnostics in Pediatric Epilepsy by Severin Schramm; Aashna Mehta; Kurtis I. Auguste; Phiroz E. Tarapore is a Medicine article available to read on EtoBox.
What is Navigated Transcranial Magnetic Stimulation Mapping of the Motor Cortex for Preoperative Diagnostics in Pediatric Epilepsy about?
## OBJECTIVE Navigated transcranial magnetic stimulation (nTMS) is a noninvasive technique often used for localization of the functional motor cortex via induction of motor evoked potentials (MEPs) in neurosurgical patients. There has, however, been no published record of its application in pediatric epilepsy surgery. In this study, the authors aimed to investigate the feasibility of nTMS-based motor mapping in the preoperative diagnostic workup within a population of children with medically refractory epilepsy. ## METHODS A single-institution database was screened for preoperative nTMS motor mappings obtained in pediatric patients (aged 0 to 18 years, 2012 to present) with medically refractory epilepsy. Patient clinical data, demographic information, and mapping results were extracted and used in statistical analyses. ## RESULTS Sixteen patients met the inclusion criteria, 15 of whom underwent resection. The median age was 9 years (range 0–17 years). No adverse effects were recorded during mapping. Specifically, no epileptic seizures were provoked via nTMS. Recordings of valid MEPs induced by nTMS were obtained in 10 patients. In the remaining patients, no MEPs could be elicited.
Who reads Navigated Transcranial Magnetic Stimulation Mapping of the Motor Cortex for Preoperative Diagnostics in Pediatric Epilepsy?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Severin Schramm; Aashna Mehta; Kurtis I. Auguste; Phiroz E. Tarapore
- Publisher
- Journal of Neurosurgery Publishing Group (JNSPG)
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)