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This document discusses thalassemia in children. It covers the functions of red blood cells, the components of hemoglobin, and genetics of thalassemia. Thalassemia is a genetic disease that results in reduced or absent globin chain synthesis, causing imbalanced globin chains. The document discusses epidemiology, mutations, inheritance patterns, phenotypes, and management of thalassemia including blood transfusions, chelation therapy, splenectomy, infection treatment and psychosocial support. Diagnosis invol

Author

Meriani Damaris Silaban

Language

EN