Can I read Astrocytes: Unveiling their role in the molecular mechanism of natural antidepressants on EtoBox?

Astrocytes: Unveiling their role in the molecular mechanism of natural antidepressants by Shimeng Lv & Ruirui Shang & Xia Zhong & Yitong Lu & Haonan Gao & Guangheng Zhang & Linghui Kong & Yunhao Yi & Yufei Huang & Yuexiang Ma & Jing Teng & Sheng Wei is a book available to read on EtoBox.

What is Astrocytes: Unveiling their role in the molecular mechanism of natural antidepressants about?

Journal of Pharmaceutical Analysis, Journal Pre-proof, 101370. doi:10.1016/j.jpha.2025.101370Abstract6 Depression, an emotional disorder characterized by persistent low mood and loss of pleasure, can be 7 alleviated by mainstream clinical drugs (such as selective serotonin reuptake inhibitors). However, 8 issues such as delayed efficacy, significant individual differences, and adverse reactions remain. 9 Compared to traditional single-target drugs, natural products have shown unique potential in 10 depression intervention due to their synergistic multi-component effects and multi-target, multi11 pathway regulation. As the most abundant glial cells in the central nervous system, astrocytes are 12 deeply involved in the pathology of depression and have become important targets for the 13 antidepressant effects of natural products. Although existing studies have revealed the regulatory 14 effects of natural products on the function of astrocytes, there is still a lack of systematic categorization 15 and mechanism integration. This review comprehensively summarized the molecular mechanisms by 16 which natural products regulated astrocyte function through a systematic literature review

Author

Shimeng Lv & Ruirui Shang & Xia Zhong & Yitong Lu & Haonan Gao & Guangheng Zhang & Linghui Kong & Yunhao Yi & Yufei Huang & Yuexiang Ma & Jing Teng & Sheng Wei

Publisher

x

Published

2025

Language

FR