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Can I read Heterotaxy-neural Tube Defect and Holoprosencephaly Occurring Independently in Two Sib Fetuses on EtoBox?

Heterotaxy-neural Tube Defect and Holoprosencephaly Occurring Independently in Two Sib Fetuses by Bonneau, Dominique; Marchaud, Martine; Odent, Sylvie; Piegay, Isabelle; Godard, Alain; Amati, Patrizia is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Heterotaxy-neural Tube Defect and Holoprosencephaly Occurring Independently in Two Sib Fetuses about?

We report on two sib fetuses, products of a consanguineous union, who had multiple and apparently unrelated malformations. The first fetus, a female, had trilobed lungs, a single cardiac ventricle, asplenia, situs ambiguus of the liver, and a lumbosacral meningomyelocele. The brain of this fetus was normal. The second fetus, a male, had bilobed lungs, a single cardiac ventricle, situs solitus of the abdominal organs and spleen, and a semilobar holoprosencephaly. The occurrence of these malformations in sibs of different sexes and the parental consanguinity suggest a recessive mutation in a gene responsible for both heterotaxy and midline defects, including holoprosencephaly.

Who reads Heterotaxy-neural Tube Defect and Holoprosencephaly Occurring Independently in Two Sib Fetuses?

It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.

Author
Bonneau, Dominique; Marchaud, Martine; Odent, Sylvie; Piegay, Isabelle; Godard, Alain; Amati, Patrizia
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); Wiley-Liss Inc; Wiley (ISSN 0148-7299)
Published
1999
Language
EN
Field
Biochemistry, Genetics and Molecular Biology (Life Sciences)