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Outcomes of COVID‐19 in hospitalized solid organ transplant recipients compared to a matched cohort of non‐transplant patients at a national healthcare system in the United States by Arielle M. Fisher; Daniel Schlauch; Matthew Mulloy; Ann Dao; Ashraf I. Reyad; Mick Correll; Gregg J. Fromell; James Pittman; Adam W. Bingaman; Balamurugan Sankarapandian; Sridhar R. Allam is a Medicine article available to read on EtoBox.

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Data describing outcomes of solid organ transplant (SOT) recipients with coronavirus disease 2019 (COVID-19) are variable, and the association between SOT status and mortality remains unclear. In this study, we compare clinical outcomes of SOT recipients hospitalized with COVID-19 between March 10, and September 1, 2020, to a matched cohort of non-SOT recipients at a national healthcare system in the United States (US). From a population of 43 461 hospitalized COVID-19-positive patients, we created a coarsened exact matched cohort of 4035 patients including 128 SOT recipients and 3907 weighted matched non-SOT controls. Multiple logistic regression was used to evaluate association between SOT status and clinical outcomes. Among the 4035 patients, median age was 60 years, 61.7% were male, 21.9% were Black/African American, and 50.8% identified as Hispanic/Latino ethnicity. Patients with a history of SOT were more likely to die within the study period when compared to matched non-SOT recipients (21.9% and 14.9%, respectively; odds ratio [OR] 1.93; 95% confidence interval [CI]: 1.18-3.15). Moreover, SOT status was associated with increased odds of receiving invasive mechanical ventilat

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Author

Arielle M. Fisher; Daniel Schlauch; Matthew Mulloy; Ann Dao; Ashraf I. Reyad; Mick Correll; Gregg J. Fromell; James Pittman; Adam W. Bingaman; Balamurugan Sankarapandian; Sridhar R. Allam

Publisher

Wiley

Published

2021

Language

EN

Field

Medicine (Health Sciences)