Can I read Genotypes of Helicobacter pylori in children with upper abdominal pain on EtoBox?

Genotypes of Helicobacter pylori in children with upper abdominal pain by MANISHA SINGH; KASHI NATH PRASAD; SURENDER KUMAR YACHHA; NARENDRA KRISHNANI is a Medicine article available to read on EtoBox.

What is Genotypes of Helicobacter pylori in children with upper abdominal pain about?

## Abstract **Background:** Studies related to genotypes of __Helicobacter pylori__ infection and upper abdominal pain (UAP) in children are scarce all over the world. We prospectively analyzed the association between __H. pylori__ infection and UAP in our study group of children and evaluated the __vacA__ genotypes associated with this disorder. **Methods:** We investigated 34 children with UAP (group I) and another 110 children as controls without UAP (group II) for __H. pylori__ infection, using antral biopsies by culture, rapid urease tests, histopathology and __ureA__ polymerase chain reaction (PCR). Genotyping was performed using specific __cagA__ and __vacA__ primers on 52 __H. pylori__ strains (group I = 21; 18 boys, mean age 10.33 ± 2.47 years; group II = 31; boys 21, mean age 9.63 ± 2.51 years). **Results:** A significant association between __H. pylori__ infection and UAP was observed when compared to controls (21/34; 61.8%__vs__ 31/110; 28.2%; __P__ = 0.0004). __cagA__ positive __H. pylori__ strains were detected in 20 (95.2%) children with UAP and in 28 (90.3%) controls. Mixed infection was detected in 25% of children with no significant difference between the groups.

Who reads Genotypes of Helicobacter pylori in children with upper abdominal pain?

Author

MANISHA SINGH; KASHI NATH PRASAD; SURENDER KUMAR YACHHA; NARENDRA KRISHNANI

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0815-9319)

Published

2003

Language

EN

Field

Medicine (Health Sciences)