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Optimized Dose Distribution of a High Dose Rate Vaginal Cylinder by Zuofeng Li D.Sc.; Chihray Liu Ph.D.; Jatinder R. Palta Ph.D. is a Medicine article available to read on EtoBox.

What is Optimized Dose Distribution of a High Dose Rate Vaginal Cylinder about?

## Purpose: To present a comparison of optimized dose distributions for a set of high-dose-rate (hdr) vaginal cylinders calculated by a commercial treatment-planning system with benchmark calculations using monte-carlo-calculated dosimetry data. ## Methods and materials: Optimized dose distributions using both an isotropic and an anisotropic dose calculation model were obtained for a set of hdr vaginal cylinders. mathematical optimization techniques available in the computer treatment-planning system were used to calculate dwell times and positions. these dose distributions were compared with benchmark calculations with tg43 formalism and using monte-carlo-calculated data. the same dwell times and positions were used for a quantitative comparison of dose calculated with three dose models. ## Results: The isotropic dose calculation model can result in discrepancies as high as 50%. the anisotropic dose calculation model compared better with benchmark calculations. the differences were more significant at the apex of the vaginal cylinder, which is typically used as the prescription point. ## Conclusion: Dose calculation models available in a computer treatment-planning system must be

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Author
Zuofeng Li D.Sc.; Chihray Liu Ph.D.; Jatinder R. Palta Ph.D.
Publisher
Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)
Published
1998
Language
EN
Field
Medicine (Health Sciences)

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