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The study investigates the protective role of heme oxygenase-1 (HO-1) against alcohol-induced liver damage, highlighting the potential of polyphenols like quercetin to enhance HO-1 expression and mitigate oxidative stress in human hepatocytes. Chronic ethanol consumption leads to increased reactive oxygen intermediates and cellular damage, but polyphenols can reduce this damage by activating protective pathways. The findings suggest that boosting HO-1 activity may offer therapeutic strategies for preventing

Author

Alada Fajayna

Language

EN