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BCAA Metabolism in KRAS-Mutant CRC by l.cherevko is a document available to read on EtoBox.

What is BCAA Metabolism in KRAS-Mutant CRC about?

The study investigates the role of branched-chain amino acids (BCAAs) in KRAS-mutant colorectal cancer (CRC), revealing that BCAA accumulation promotes cell proliferation through the downregulation of enoyl-CoA hydratase-1 (ECHS1). Restricting BCAA supply inhibits the proliferation of KRAS-mutant CRC cells without affecting metastasis, and ECHS1

Author

l.cherevko

Language

EN