About this Immunology and Microbiology article

Impact of acute stress on antimicrobial polypeptides mRNA copy number in several tissues of marine sea bass ( Dicentrarchus labrax ) by Genciana Terova; Anna G Cattaneo; Elena Preziosa; Giovanni Bernardini; Marco Saroglia is a Immunology and Microbiology article available to read on EtoBox.

## Background In comparison to higher vertebrates, fish are thought to rely heavily on innate immune system for initial protection against pathogen invasion because their acquired immune system displays a considerably poor immunological memory, and short-lived secondary response. The endogenous antimicrobial polypeptides (AMPPs) directly and rapidly killing pathogens such as bacteria, fungi, parasites, and viruses are included within the realm of innate defenses. In addition to piscidins, AMPPs that in recent years have been shown to be commonly linked to innate defense, are histones and their polypeptide fragments, and peptides derived from the respiratory protein hemoglobin. There is evidence that a number of stresses lead to significant regulation of AMPPs and thus their monitoring could be a highly sensitive measure of health status and risk of an infectious disease outbreak, which is a major impediment to the continued success of virtually all aquaculture enterprises and is often the most significant cause of economic losses. ## Results We firstly isolated and deposited in Genbank database the cDNA sequences encoding for __hemoglobin-β-like protein__ (__Hb-LP__) [GeneBank: JN4

Author

Genciana Terova; Anna G Cattaneo; Elena Preziosa; Giovanni Bernardini; Marco Saroglia

Publisher

BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2000-; Springer Science and Business Media LLC (ISSN 1471-2172)

Published

2011

Language

EN

Field

Immunology and Microbiology (Life Sciences)