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PEGylated Protein Drugs: Basic Science and Clinical Applications by Veronese, Francesco M. is a scholarly article available to read on EtoBox.

What is PEGylated Protein Drugs: Basic Science and Clinical Applications about?

PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.

Author

Veronese, Francesco M.

Publisher

Birkhäuser Basel

Published

2009

Language

EN

ISBN

9783764386788