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Can I read Connectome Analysis of Brain Functional Network Alterations in Breast Cancer Survivors with and Without Chemotherapy on EtoBox?
Connectome Analysis of Brain Functional Network Alterations in Breast Cancer Survivors with and Without Chemotherapy by Chen, Vincent Chin-Hung; Lin, Kai-Yi; Tsai, Yuan-Hsiung; Weng, Jun-Cheng; Zhang, Han is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Connectome Analysis of Brain Functional Network Alterations in Breast Cancer Survivors with and Without Chemotherapy about?
## Purpose Treatment modalities for breast cancer, the leading cause of cancer-related deaths in women worldwide, include surgery, radiotherapy, adjuvant chemotherapy, targeted therapy, and hormonal therapy. The advancement in medical technology has facilitated substantial reduction in breast cancer mortality. However, patients may experience cognitive impairment after chemotherapy. This phenomenon called chemotherapy-induced cognitive impairment (i.e., “chemobrain”) is common among breast cancer survivors. However, cognitive function deficits may exist before chemotherapy initiation. This study examined the functional network alterations in breast survivors by using resting-state functional magnetic resonance imaging (fMRI). ## Methods We recruited 172 female participants and separated them into three groups: C+ (57 breast cancer survivors who had finished 3–12-month-long chemotherapy), C- (45 breast cancer survivors who had not undergone chemotherapy), and HC (70 participants with no breast cancer history). We analyzed mean fractional amplitudes of low-frequency fluctuation and graph theoretical topologies from resting-state fMRI and applied network-based analysis to portray func
Who reads Connectome Analysis of Brain Functional Network Alterations in Breast Cancer Survivors with and Without Chemotherapy?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Chen, Vincent Chin-Hung; Lin, Kai-Yi; Tsai, Yuan-Hsiung; Weng, Jun-Cheng; Zhang, Han
- Publisher
- Public Library of Science; San Francisco CA: Public Library of Science; Publons; ScienceOpen; Public Library of Science (PLoS) (ISSN 1932-6203)
- Published
- 2020
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)