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Differential Impact of Fractional Flow Reserve Measured After Coronary Stent Implantation by Left Ventricular Dysfunction by Ki Hong Choi; Woochan Kwon; Doosup Shin; Seung-Hun Lee; Doyeon Hwang; Jinlong Zhang; Chang-Wook Nam; Eun-Seok Shin; Joon-Hyung Doh; Shao-Liang Chen; Tsunekazu Kakuta; Gabor G. Toth; Zsolt Piroth; Abdul Hakeem; Barry F. Uretsky; Yohei Hokama; Nobuhiro Tanaka; Hong-Seok Lim; Tsuyoshi Ito; Akiko Matsuo; Lorenzo Azzalini; Massoud A. Leesar; Joost Daemen; Damien Collison; Carlos Collet; Bernard De Bruyne; Bon-Kwon Koo; Taek Kyu Park; Jeong Hoon Yang; Young Bin Song; Joo-Yong Hahn; Seung-Hyuk Choi; Hyeon-Cheol Gwon; Joo Myung Lee is a Medicine article available to read on EtoBox.

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## Background Both left ventricular systolic function and fractional flow reserve (FFR) are prognostic factors after percutaneous coronary intervention (PCI). However, how these prognostic factors are inter-related in risk stratification of patients after PCI remains unclarified. ## Objectives This study evaluated differential prognostic implication of post-PCI FFR according to left ventricular ejection fraction (LVEF). ## Methods A total of 2,965 patients with available LVEF were selected from the POST-PCI FLOW (Prognostic Implications of Physiologic Investigation After Revascularization with Stent) international registry of patients with post-PCI FFR measurement. The primary outcome was a composite of cardiac death or target-vessel myocardial infarction (TVMI) at 2 years. The secondary outcome was target-vessel revascularization (TVR) and target vessel failure, which was a composite of cardiac death, TVMI, or TVR. ## Results Post-PCI FFR was independently associated with the risk of target vessel failure (per 0.01 decrease: HR~adj~: 1.029; 95% CI: 1.009-1.049; __P =__ 0.005). Post-PCI FFR was associated with increased risk of cardiac death or TVMI (HR~adj~: 1.145; 95% CI: 1.025-1

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Author

Ki Hong Choi; Woochan Kwon; Doosup Shin; Seung-Hun Lee; Doyeon Hwang; Jinlong Zhang; Chang-Wook Nam; Eun-Seok Shin; Joon-Hyung Doh; Shao-Liang Chen; Tsunekazu Kakuta; Gabor G. Toth; Zsolt Piroth; Abdul Hakeem; Barry F. Uretsky; Yohei Hokama; Nobuhiro Tanaka; Hong-Seok Lim; Tsuyoshi Ito; Akiko Matsuo; Lorenzo Azzalini; Massoud A. Leesar; Joost Daemen; Damien Collison; Carlos Collet; Bernard De Bruyne; Bon-Kwon Koo; Taek Kyu Park; Jeong Hoon Yang; Young Bin Song; Joo-Yong Hahn; Seung-Hyuk Choi; Hyeon-Cheol Gwon; Joo Myung Lee

Publisher

Elsevier BV

Published

2024

Language

EN

Field

Medicine (Health Sciences)