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How is early spondyloarthritis defined in the literature? Results from a systematic review by Diego Benavent; Dafne Capelusnik; Désirée van der Heijde; Robert Landewé; Denis Poddubnyy; Astrid van Tubergen; Louise Falzon; Sofia Ramiro; Victoria Navarro-Compán is a Medicine article available to read on EtoBox.

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## Aim: To identify all possible definitions of "early spa" employed in the literature, including "early axial spa (axspa)" and "early peripheral spa (pspa)". ## Methods: A systematic literature review was conducted in medline, embase and the cochrane library for studies that included any mention of "early spa" or its subtypes. the proportion of studies including a definition was calculated, and the different definitions were assessed. ## Results: Out of 9651 titles identified, 336 publications reporting data from 183 studies were included. over time, an increasing number of publications were identified. in total, 114 (62%) studies reported a specific definition: 33% of them based it on symptom duration, 31% on radiographic damage, 28% on disease duration, 5% on both symptom/disease duration and radiographic damage, and 3% on other aspects. overall, 61 (33%) studies included the term "early axspa", whereas 60 (33%) included "early ankylosing spondylitis (as)". regarding the studies that referred to "early axspa", the most used definition was symptom/disease duration <5 years, whereas for "early as" was symptom/disease duration <10 years. after 2010, the definition of "early axspa"

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Author

Diego Benavent; Dafne Capelusnik; Désirée van der Heijde; Robert Landewé; Denis Poddubnyy; Astrid van Tubergen; Louise Falzon; Sofia Ramiro; Victoria Navarro-Compán

Publisher

Elsevier BV

Published

2022

Language

EN

Field

Medicine (Health Sciences)