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Highly localized positive contrast of small paramagnetic objects using 3D center-out radial sampling with off-resonance reception by Peter R. Seevinck; Hendrik de Leeuw; Clemens Bos; Chris J. G. Bakker is a Medicine article available to read on EtoBox.

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## Abstract In this article, we present a 3D imaging technique, applying center‐out RAdial Sampling with Off‐Resonance reception, to accurately depict and localize small paramagnetic objects with high positive contrast while suppressing long T~2~^\*^ components. The center‐out RAdial Sampling with Off‐Resonance reception imaging technique is a fully frequency‐encoded 3D ultrashort echo time acquisition method, which uses a large excitation bandwidth and off‐resonance reception. By manually introducing an offset, Δ__f__~0~, to the central reception frequency (__f__~0~), the typical radial signal pileup observed in 3D center‐out sampling caused by a dipolar magnetic field disturbance can be shifted toward the source of the field disturbance, resulting in a hyperintense signal at the magnetic center of the small paramagnetic object. This was demonstrated both theoretically and using 1D time domain simulations. Experimental verification was done in a gel phantom and in inhomogeneous porcine tissue containing various objects with very different geometry and susceptibility, namely, subvoxel stainless steel spheres, a puncture needle, and paramagnetic brachytherapy seeds. In all cases, ce

Who reads Highly localized positive contrast of small paramagnetic objects using 3D center-out radial sampling with off-resonance reception?

Author

Peter R. Seevinck; Hendrik de Leeuw; Clemens Bos; Chris J. G. Bakker

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0740-3194)

Published

2010

Language

EN

Field

Medicine (Health Sciences)