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Can I read Nodal Positivity in Clinically Node-negative Breast Cancer Following Neoadjuvant Chemotherapy on EtoBox?
Nodal Positivity in Clinically Node-negative Breast Cancer Following Neoadjuvant Chemotherapy by Alexandra Zaborowski; Katie Doogan; Karina Delaney; Farah Kazi; Aaron Brady; Gavin Dowling; Siobhan Clifford; Peter O'Leary; Terry Boyle; Dhafir Alazawi; Elizabeth Connolly; Colm Power; Arnold Hill; Anna Heeney; Siun Walsh; Maurice Stokes; Mitchel Barry; Malcolm Kell; Jane Rothwell; Denis Evoy; James Geraghty; Damian McCartan; Ruth Prichard is a Medicine article available to read on EtoBox.
What is Nodal Positivity in Clinically Node-negative Breast Cancer Following Neoadjuvant Chemotherapy about?
Background: Breast cancer is the commonest cancer worldwide with remarkable advances in diagnosis, early detection, systemic treatments, and surgical techniques. Robotic nipple-sparing mastectomy (RNSM) has been trialled, however complication rates, oncological safety and operative variables of this approach remain obscure. Materials and methods: A systematic search of the literature was conducted from conception till September 2022. Cohort studies and randomized control trials examining complications and operative variables comparing RNSM to open NSM were included. The primary outcome was comparing Grade 3 complications while the secondary outcomes included operative variables. Results: Seven studies of overall fair quality, involving 1014 patients were included in the systematic review and meta-analysis. Overall, grade 3 complications (re-operation, Skin necrosis, Seroma and Haematoma) were reduced in RNSM but not reaching statistical significance Odds Ratio 0.60 [0.35, 1.05]. There was no difference for wound dehiscence 1.08[0.52, 2.25], however, nipple necrosis was significantly less in RNSM 0. 70[0.40, 1.23].Whilst not statistically significant, post-operative infections OR 1.
Who reads Nodal Positivity in Clinically Node-negative Breast Cancer Following Neoadjuvant Chemotherapy?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Alexandra Zaborowski; Katie Doogan; Karina Delaney; Farah Kazi; Aaron Brady; Gavin Dowling; Siobhan Clifford; Peter O'Leary; Terry Boyle; Dhafir Alazawi; Elizabeth Connolly; Colm Power; Arnold Hill; Anna Heeney; Siun Walsh; Maurice Stokes; Mitchel Barry; Malcolm Kell; Jane Rothwell; Denis Evoy; James Geraghty; Damian McCartan; Ruth Prichard
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)