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Home Versus Ambulatory and Office Blood Pressure in Predicting Target Organ Damage in Hypertension: a Systematic Review and Meta-analysis by Ioannis A. Bliziotis; Antonis Destounis; George S. Stergiou is a Medicine article available to read on EtoBox.

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Studies have shown that ambulatory blood pressure (BP) is more closely related to preclinical target organ damage than office measurements. A review and meta-analysis of studies investigating the association of home BP measurements with target organ damage was performed. Methods: A PubMed and Cochrane Library search revealed 23 studies reporting comparative data of home BP versus ambulatory and/or office measurements in terms of their association with several indices of target organ damage. Correlation coefficients were pooled by random-effects model meta-analysis. Results: Fourteen studies (n 1⁄4 2485) assessing echocardiographic left ventricular mass index (LVMI) showed similar correlations with home (coefficients r 1⁄4 0.46/0.28, systolic/diastolic) as with ambulatory BP (0.37/0.26, P 1⁄4 NS for difference versus home BP), and superior to office measurements (r 1⁄4 0.23/0.19, P < 0.001/0.009 for difference versus home BP). Four methodologically heterogeneous studies assessing the glomerular filtration rate (n 1⁄4 609) could not be pooled or lead to a concrete result. Four studies assessing carotid intima-media thickness (n 1⁄4 1222), three assessing pulse wave velocity (n 1⁄4 72

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Author

Ioannis A. Bliziotis; Antonis Destounis; George S. Stergiou

Publisher

Ovid Technologies (Wolters Kluwer Health)

Published

2012

Language

EN

Field

Medicine (Health Sciences)