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Patients with nasopharyngeal carcinoma (NPC) represent a distinctin both locoregional relapse and survival with this de‐intensificationgroup with head and neck cancer. They are often nontobacco users,approach, should the use of the post‐IC GTV for intensity‐nonalcohol users, and on average are 10 to 20 years younger thanmodulated radiotherapy planning be adopted universally? Beforepatients with cancers of other head and neck sites. Given goodwe make a conclusion, let us first examine some fundamental quesbaseline health status and the effectiveness of contemporary treattions in NPC treatment.ment,1–3 patients with NPC typically have long projected life exFirst, does chemosensitivity equate with radiosensitivity? Inpectancies and commonly develop late treatment effects, such asthese studies, the determination for radiosensitivity was based oncranial nerve deficits and dysphagia. Previous efforts in reducingchemosensitivity. It is important to recognize that chemosensitivityradiation‐related toxicity included the use of reduced target doses4does not necessarily correlate with radiosensitivity. The molecularand volumes.3,5–8

Author

x

Published

2025

Language

EN