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Evolution of the Local Calcium Content Around Irradiated β-Tricalcium Phosphate Ceramic Implants: in Vivo Study in the Rabbit by J.C. Le Huec; D. Clément; B. Brouillaud; N. Barthe; B. Dupuy; B. Foliguet; B. Basse-Cathalinat is a Engineering article available to read on EtoBox.

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To evaluate whether dissolved calcium from tricalcium phosphate implants contributes to osseous wound healing in bone defects, the authors used nuclear radioactivated materials. Six months after irradiation, the calcium was still radioactive. Samples of the material were prepared and placed in rabbit condyles for 1, 3 and 9 months. Over time the condyles were retrieved and treated for histology or radiocounting. Measurements of the radioactivity of the slices and histomorphometry of the implants and surrounding tissues were performed. The authors observed that the radioactivity decreased regularly. Connective tissue had penetrated the pores and totally invaded the implants, first at the periphery of the implants, then inside the pores. Comparison of the results of radioactivity and histomorphometry suggest that part of the calcium from the implants was re-used specifically in the new osseous tissue.

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Author

J.C. Le Huec; D. Clément; B. Brouillaud; N. Barthe; B. Dupuy; B. Foliguet; B. Basse-Cathalinat

Publisher

Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0142-9612)

Published

1998

Language

EN

Field

Engineering (Physical Sciences)