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An Analytical Approach to the Protein Designability Problem by Kussell, Edo L.; Shakhnovich, Eugene I. is a scholarly article available to read on EtoBox.

What is An Analytical Approach to the Protein Designability Problem about?

We present an analytical method for determining the designability of protein structures. We apply our method to the case of two-dimensional lattice structures, and give a systematic solution for the spectrum of any structure. Using this spectrum, the designability of a structure can be estimated. We outline a heirarchy of structures, from most to least designable, and show that this heirarchy depends on the potential that is used.

Author

Kussell, Edo L.; Shakhnovich, Eugene I.

Published

1999

Language

EN