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What is JAK1/JAK2 Role in Coccidioidomycosis Defense about?

This case report highlights the significance of JAK1 and JAK2 gene transcription in antifungal defense, particularly in a patient with pulmonary coccidioidomycosis undergoing ruxolitinib therapy for polycythemia vera. The patient experienced a relapse of the infection after discontinuing antifungal treatment while continuing ruxolitinib, emphasizing the need for ongoing monitoring and the critical role of the JAK-STAT pathway in immune response against fungal infections. The findings suggest that clinicians

Author

CT DAM

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EN