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Gastric emptying in health and type 2 diabetes: An evaluation using a 75 g oral glucose drink by Xie, Cong; Huang, Weikun; Wang, Xuyi; Trahair, Laurence G.; Pham, Hung T.; Marathe, Chinmay S.; Young, Richard L.; Jones, Karen L.; Horowitz, Michael; Rayner, Christopher K.; Wu, Tongzhi is a Medicine article available to read on EtoBox.
What is Gastric emptying in health and type 2 diabetes: An evaluation using a 75 g oral glucose drink about?
## Aim: Gastric emptying is a major determinant of the glycaemic response to carbohydrate and is frequently abnormal in type 2 diabetes (t2dm). there is little information about how chronic glycaemic control affects gastric emptying in t2dm. we evaluated gastric emptying of a 75 g glucose drink in community-based patients with t2dm of short duration with good or poor glycaemic control, and compared this to young and older controls. ## Methods: T2dm patients managed by diet and/or metformin, either well-controlled or poorly-controlled, together with young and age-matched older controls without diabetes, consumed a 75 g oral glucose drink containing 150 mg c-acetate for evaluation of gastric emptying (breath test) and blood glucose over 180 min. ## Results: The gastric half-emptying time (t50) was longer in the older than the young non-diabetic subjects (p = 0.041), but shorter in well-controlled t2dm patients than age-matched older controls (p = 0.043). the t50 in poorly-controlled t2dm patients was shorter than in older controls (p = 0.006), but similar to young non-diabetic subjects. ## Conclusions: Gastric emptying of a glucose drink is delayed with ageing, but more rapid in pati
Who reads Gastric emptying in health and type 2 diabetes: An evaluation using a 75 g oral glucose drink?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Xie, Cong; Huang, Weikun; Wang, Xuyi; Trahair, Laurence G.; Pham, Hung T.; Marathe, Chinmay S.; Young, Richard L.; Jones, Karen L.; Horowitz, Michael; Rayner, Christopher K.; Wu, Tongzhi
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0168-8227)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)