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A Subluxing Arthropathy Associated with the Anti-jo-1 Antibody in Polymyositis/dermatomyositis by Chester V. Oddis; Thomas A. Medsger Jr; Lawrence A. Cooperstein is a Medicine article available to read on EtoBox.

What is A Subluxing Arthropathy Associated with the Anti-jo-1 Antibody in Polymyositis/dermatomyositis about?

Of 180 patients with polymyositis/dermatomyositis (PM/DM) seen at the University of Pittsburgh and affiliated hospitals since 1975, 21 of 100 tested positive for the anti-Jo-1 antibody. Sixteen of the 21 patients were women and 18 were white. Fifteen had adult PM, 4 had myositis in overlap with scleroderma, and 2 had adult DM. Evidence of interstitial lung disease was found in 12 of 18 anti-Jo-1 positive patients (67%), but in only 15 of 79 anti-Jo-1 negative patients (19%) (P < 0.0002). The 21 anti-,To-1 positive patients were divided into 3 separate groups based on the observed articular findings. Four patients had a deforming, predominantly nonerosive arthropathy with subluxations of the distal interphalangeal joints, especially the thumbs. Eight patients had a nondeforming arthropathy primarily affecting the small joints of the hands, wrists, shoulders, and knees. Those with deformities had a longer duration From the Division of Rheumatology and Clinical Immunology and the Division of

Who reads A Subluxing Arthropathy Associated with the Anti-jo-1 Antibody in Polymyositis/dermatomyositis?

Author

Chester V. Oddis; Thomas A. Medsger Jr; Lawrence A. Cooperstein

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0004-3591)

Published

1990

Language

EN

Field

Medicine (Health Sciences)