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Corticosteroids for Acute Bacterial Meningitis by Brian R.E. Schultz; Coburn H. Allen; Sheldon L. Kaplan is a Medicine article available to read on EtoBox.

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reported using or planning an early goal-directed therapy protocol. The decision to perform early goal-directed therapy confronts providers on a daily basis regardless of hospital location. Disproportionally, nearly 60-75% of severe sepsis patients present through the ED averaging 150-400 patients per year with stays of 4-5 hours. Assuming a 16% absolute mortality risk reduction and an estimated 571,000 septic patients presenting to the ED per year, 6 choosing not to perform early goal-directed therapy may result in an additional 91,000 lives lost per year. While logistical and professional challenges regarding early goal-directed therapy implementation exist, these are similar and were overcome in the evolution of care for trauma, acute myocardial infarction and stroke. Despite the challenges, the common theme is that "time is tissue" and delayed recognition or suboptimal treatment of organ failure and shock states adversely impacts morbidity and mortality. Prior to the early goal-directed therapy study and the Surviving Sepsis Campaign, one could reasonably argue that there was no standard of care for severe sepsis, especially in the early setting. Future studies are likely to

Who reads Corticosteroids for Acute Bacterial Meningitis?

Author

Brian R.E. Schultz; Coburn H. Allen; Sheldon L. Kaplan

Publisher

Elsevier Science; Elsevier ; Mosby Inc.; Elsevier BV (ISSN 1097-6760)

Published

2009

Field

Medicine (Health Sciences)