Can I read Evaluation of a Pig Femoral Head Osteonecrosis Model on EtoBox?

Evaluation of a Pig Femoral Head Osteonecrosis Model by Ping Zhang; Yun Liang; Harry Kim; Hiroki Yokota is a Medicine article available to read on EtoBox.

What is Evaluation of a Pig Femoral Head Osteonecrosis Model about?

## Abstract ## Background A major cause of osteonecrosis of the femoral head is interruption of a blood supply to the proximal femur. In order to evaluate blood circulation and pathogenetic alterations, a pig femoral head osteonecrosis model was examined to address whether ligature of the femoral neck (vasculature deprivation) induces a reduction of blood circulation in the femoral head, and whether transphyseal vessels exist for communications between the epiphysis and the metaphysis. We also tested the hypothesis that the vessels surrounding the femoral neck and the ligamentum teres represent the primary source of blood flow to the femoral head. ## Methods Avascular osteonecrosis of the femoral head was induced in Yorkshire pigs by transecting the ligamentum teres and placing two ligatures around the femoral neck. After heparinized saline infusion and microfil perfusion via the abdominal aorta, blood circulation in the femoral head was evaluated by optical and CT imaging. ## Results An angiogram of the microfil casted sample allowed identification of the major blood vessels to the proximal femur including the iliac, common femoral, superficial femoral, deep femoral and circumflex

Who reads Evaluation of a Pig Femoral Head Osteonecrosis Model?

Author

Ping Zhang; Yun Liang; Harry Kim; Hiroki Yokota

Publisher

BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2006-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1749-799X)

Published

2010

Language

EN

Field

Medicine (Health Sciences)