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Drug Discovery via Transcriptional Signatures by ampere.engmanutencao is a document available to read on EtoBox.
What is Drug Discovery via Transcriptional Signatures about?
The document presents a novel in silico approach for drug discovery called connectivity enhanced structure activity relationship (ceSAR), which integrates transcriptional signature connectivity with molecular docking to improve the identification of candidate compounds. By leveraging the LINCS library of transcriptional signatures, ceSAR significantly reduces false-positive rates and computational costs while enhancing the drug discovery process. The effectiveness of ceSAR is demonstrated through the identi
- Author
- ampere.engmanutencao
- Language
- EN