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This research note discusses a retrospective study of 15 patients with endocarditis who were treated with high doses of b-lactams, monitoring their trough plasma concentrations using high-performance liquid chromatography (HPLC). The study highlights that elderly patients often achieve higher plasma concentrations, which may lead to increased toxicity, and that monitoring b-lactam levels could improve treatment efficacy and tolerance. The findings indicate that despite the use of high doses, the relationshi

Author

Bruno Félix Mendes

Language

EN