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Can I read Chronic anorexic and behavioural effects of the fenfluramine derivative SE 780 in rats on EtoBox?
Chronic anorexic and behavioural effects of the fenfluramine derivative SE 780 in rats by M. Taylor; A. J. Goudie is a Neuroscience article available to read on EtoBox.
What is Chronic anorexic and behavioural effects of the fenfluramine derivative SE 780 in rats about?
The behavioural and anorexic effects of the fenfluramine derivative "SE 780" in rats were studied after chronic administration over 35 days. Behavioural effects of the compound were assessed by "time sampling" behavioural categorisation, on days 1, 14 and 28 of administration. An initial sedative effect observed after acute administration was absent on days 14 and 28 of observation, when the drug had no behavioural effects at all. The anorexic properties of the drug were investigated in two ways. Firstly, by measuring daily body weights; and secondly by measuring intake of food over a 2 h period on observation days. The drug appeared to be a highly potent anorexiant in that tolerance to its effects built up very slowly. It is suggested that SE 780 may be an anorexic agent which is superior to Fenfluramine in two ways; firstly, it lacks stimulant properties after chronic administration, and secondly it is active over longer periods of time; as such it merits further study in humans.
Who reads Chronic anorexic and behavioural effects of the fenfluramine derivative SE 780 in rats?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- M. Taylor; A. J. Goudie
- Publisher
- Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 0033-3158)
- Published
- 1974
- Language
- EN
- Field
- Neuroscience (Life Sciences)