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Can I read Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels on EtoBox?
Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels by Li, Yuanyuan; Cai, Zhaochong; Liu, Shunjie; Zhang, Haoke; Wong, Sherman T. H.; Lam, Jacky W. Y.; Kwok, Ryan T. K.; Qian, Jun; Tang, Ben Zhong is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels about?
Fluorescence imaging in near-infrared IIb (NIR-IIb, 1500–1700 nm) spectrum holds a great promise for tissue imaging. While few inorganic NIR-IIb fluorescent probes have been reported, their organic counterparts are still rarely developed, possibly due to the shortage of efficient materials with long emission wavelength. Herein, we propose a molecular design philosophy to explore pure organic NIR-IIb fluorophores by manipulation of the effects of twisted intramolecular charge transfer and aggregation-induced emission at the molecular and morphological levels. An organic fluorescent dye emitting up to 1600 nm with a quantum yield of 11.5% in the NIR-II region is developed. NIR-IIb fluorescence imaging of blood vessels and deeply-located intestinal tract of live mice based on organic dyes is achieved with high clarity and enhanced signal-to-background ratio. We hope this study will inspire further development on the evolution of pure organic NIR-IIb dyes for bio-imaging.
Who reads Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Li, Yuanyuan; Cai, Zhaochong; Liu, Shunjie; Zhang, Haoke; Wong, Sherman T. H.; Lam, Jacky W. Y.; Kwok, Ryan T. K.; Qian, Jun; Tang, Ben Zhong
- Publisher
- Nature Publishing Group; Springer Science and Business Media LLC; [London]: Nature Publishing Group, 2010-; Society for Mining, Metallurgy and Exploration Inc.; Research Square (ISSN 2041-1723)
- Published
- 2020
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)