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Quantitative evaluation of the fibrin clot extension on different implant surfaces: An in vitro study by Donato Di Iorio; Tonino Traini; Marco Degidi; Sergio Caputi; Joerg Neugebauer; Adriano Piattelli is a Medicine article available to read on EtoBox.

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## Abstract The aim of the present study was a quantitative evaluation of the __in vitro__ fibrin clot extension on different implant surfaces. Forty‐five disk‐shaped commercially pure Grade 2 titanium samples with three different surface topographies (machined, DPS, and Plus) were used in the present study. For the quantitative evaluation of the fibrin clot, 30 specimens were used (10 per group); human whole blood was employed. Venous blood was drawn from three healthy adult volunteers, and 0.2 mL were immediately dropped onto the surface of each specimen. Contact time was 5 min at room temperature; then the samples were rinsed with saline solution and fixed in a buffered solution of glutaraldehyde and paraformaldehyde. Samples were washed again with buffer and dehydrated in an ascending alcohol series. Specimens belonging to all groups were observed under SEM at a magnification of 1000×. From each sample, 50 random micrographs were collected in .tif format with an N × M 1024 × 768 grid of pixels. Quantitative analysis of fibrin clot extension showed the following results: in machined samples fibrin clot extension was 345987.2 ± 63747.7 pixels^2^ (mean ± SD), in DPS samples fibrin

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Author
Donato Di Iorio; Tonino Traini; Marco Degidi; Sergio Caputi; Joerg Neugebauer; Adriano Piattelli
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1552-4973)
Published
2005
Language
EN
Field
Medicine (Health Sciences)

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