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Transplantation of Autologous Endothelial Cells Induces Angiogenesis by VALERI CHEKANOV; MASSOD AKHTAR; GUENNADY TCHEKANOV; GEORGE DANGAS; MUHAMMAD Z. SHEHZAD; FERMIN TIO; MILENA ADAMIAN; ANTONIO COLOMBO; GARY ROUBIN; MARTIN B. LEON; JEFFREY W. MOSES; NICHOLAS N. KIPSHIDZE is a Medicine article available to read on EtoBox.

What is Transplantation of Autologous Endothelial Cells Induces Angiogenesis about?

**CHEKANOV, V., et al.: Transplantation of Autologous Endothelial Cells Induces Angiogenesis.** __This study examined the feasibility and efficacy of autologous endothelial cell (EC) transplantation using a fibrin matrix in the ischemic myocardium of sheep. Four weeks after placing an ameroid constrictor in the circumflex artery of 12 adult sheep, four animals (EC group) were subjected to EC transplantation. In four others (saline [SAL] group) saline with added inactivated cells was injected and four animals served as controls. Eight weeks after treatment the animals were sacrificed to assess histology and ultrastructure. Eight weeks after injection, ventricular function was markedly improved in the EC transplant group, but had deteriorated in the SAL and control groups. Myocardial blood flow was also increased in the EC group. Histology and electron microscopy revealed extensive neovascularization after EC transplantation and improved myocardial appearance. Heterotopic transplantation of EC within a fibrin matrix enhances neovascularization, increases myocardial blood flow, and improves left ventricular function. (PACE 2003; 26[Pt. II]:496–499)__

Who reads Transplantation of Autologous Endothelial Cells Induces Angiogenesis?

It is typically read by researchers, students, and practitioners in Medicine.

Author
VALERI CHEKANOV; MASSOD AKHTAR; GUENNADY TCHEKANOV; GEORGE DANGAS; MUHAMMAD Z. SHEHZAD; FERMIN TIO; MILENA ADAMIAN; ANTONIO COLOMBO; GARY ROUBIN; MARTIN B. LEON; JEFFREY W. MOSES; NICHOLAS N. KIPSHIDZE
Publisher
John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0147-8389)
Published
2003
Language
EN
Field
Medicine (Health Sciences)

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