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What is 07 The Roles of E3 Ubiquitin Ligases in Cancer Progression and Targeted Therapy. about?

This review discusses the critical roles of E3 ubiquitin ligases in cancer progression and their potential as targets for cancer therapy. It highlights how E3 ligases influence various cancer-related pathways, including cell cycle progression, immune evasion, and apoptosis escape, and summarizes the development of small molecule inhibitors aimed at these ligases. The review also categorizes E3 ligases into three families: RING, HECT, and RBR, detailing their mechanisms and implications in cancer treatment.

Author

cocolasym13

Language

EN