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Sample preparation methods for N-glycomics by H. Mehmet Kayili; Mehmet Atakay; Ali Hayatu; Bekir Salih is a Chemistry article available to read on EtoBox.

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Aberrant glycosylation has been associated with the human disease since it involves crucial mechanisms such as tumor onset, development, and progression. This review focuses on the most commonly used sample preparation methods for standard glycoprotein, serum, cell, and tissue samples in N-glycan analysis studies. We aim to provide readers with an overview of N-glycomics sample preparation methods for profiling N-glycans. From this perspective, this review illustrates the main strategies of N-glycan analysis using different techniques. The molecular information obtained from glycomics analysis has allowed new visions into the mechanism concerning aberrant glycosylation.

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Author

H. Mehmet Kayili; Mehmet Atakay; Ali Hayatu; Bekir Salih

Publisher

Elsevier BV

Published

2022

Language

EN

Field

Chemistry (Physical Sciences)