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Synthesis, rheological characterization, and antibacterial activity of polyvinyl alcohol (PVA)/ zinc oxide nanoparticles wound dressing, achieved under electron beam irradiation by Mina Arab; Mojtaba Jallab; Mehdi Ghaffari; Ehsan Moghbelli; Mohammad Reza Saeb is a Materials Science article available to read on EtoBox.

What is Synthesis, rheological characterization, and antibacterial activity of polyvinyl alcohol (PVA)/ zinc oxide nanoparticles wound dressing, achieved under electron beam irradiation about?

An antibacterial wound dressing hydrogel was synthesized from biopolymers and a semiconductor nanomaterial by gamma irradiation, and applied in a simulated environment. Polyvinyl alcohol (PVA)/agar hydrogel was chosen due to its biocompatibility and good swelling to absorb wound exudates and make a moist environment to accelerate the wound healing process. Zinc oxide nanoparticles were synthesized and combined with the hydrogel due to their antibacterial activity as a wound dressing aid and the hydrophilic nature to enhance swelling capacity by facilitating water flow in the hydrogel. Hydrogel samples based on PVA/agar containing low amounts of zinc oxide nanoparticles were prepared by gamma irradiation to meet all the requirements of a wound dressing. Water absorption, swelling behavior and pH sensitivity were studied and showed an excellent water swelling capacity. Scanning electron microscopy (SEM) and UV-Vis spectroscopy analyses were employed, where dispersion state of nanoparticles played a key role. Antibacterial activity mechanisms and the resistance to gram-positive bacteria were tested by the disk diffusion method, and the developed hydrogel revealed resistance against gr

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Author

Mina Arab; Mojtaba Jallab; Mehdi Ghaffari; Ehsan Moghbelli; Mohammad Reza Saeb

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Materials Science (Physical Sciences)