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Effect of Size and Silica Coating on Structural, Magnetic as Well as Cytotoxicity Properties of Copper Ferrite Nanoparticles by Lavanya Khanna; Garima Gupta; S.K. Tripathi is a Engineering article available to read on EtoBox.

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Copper ferrite nanoparticles, synthesized by conventional sol-gel method were calcined at different temperatures. The magnetic, structural, morphological and cytotoxicity analyses of the uncalcined and calcined nanoparticles (NPs) were investigated and compared. Formation of tetragonal structure of CuFeO NPs was observed in XRD patterns. On increasing the temperature, better crystallinity and increased crystallite size were also observed. In the FTIR spectra, bonds corresponding to CH, OH and carboxylate groups gradually disappeared with increasing temperature, while peak corresponding to FeO existed more prominently. NPs calcined at 300 °C (Cu3) exhibited the highest magnetic saturation and lowest retentivity, thereby indicating its superparamagnetic behaviour. Concentration-dependent cytotoxicity values were obtained by invitro MTT (3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide, a tetrazole) assay, Cell Titer assay and Cell Flow Cytometry with Propidium Iodide. NPs calcined at 300 °C, 500 °C and 700 °C exhibited non-toxicity at all the concentrations. Based on magnetic and biocompatibility analyses, Cu3 NPs were found to be the most suitable one to investigate th

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Author

Lavanya Khanna; Garima Gupta; S.K. Tripathi

Publisher

Elsevier BV

Published

2019

Language

EN

Field

Engineering (Physical Sciences)