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What is CML Monitoring: ddPCR vs qPCR Analysis about?
This study compares the effectiveness of droplet digital PCR (ddPCR) and quantitative PCR (qPCR) in measuring BCR-ABL1/ABL1 p210 levels for monitoring chronic myeloid leukemia (CML) patients. Results indicate excellent qualitative and quantitative correlations between the two methods, with a Kappa index of 0.94 and an intra-class correlation coefficient of 0.868, confirming that ddPCR does not significantly increase sensitivity over qPCR. The findings support the use of both techniques for molecular monitor
- Author
- Hiu Hiu
- Language
- EN