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CML Monitoring: ddPCR vs qPCR Analysis by Hiu Hiu is a document available to read on EtoBox.

What is CML Monitoring: ddPCR vs qPCR Analysis about?

This study compares the effectiveness of droplet digital PCR (ddPCR) and quantitative PCR (qPCR) in measuring BCR-ABL1/ABL1 p210 levels for monitoring chronic myeloid leukemia (CML) patients. Results indicate excellent qualitative and quantitative correlations between the two methods, with a Kappa index of 0.94 and an intra-class correlation coefficient of 0.868, confirming that ddPCR does not significantly increase sensitivity over qPCR. The findings support the use of both techniques for molecular monitor

Author
Hiu Hiu
Language
EN