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pKa Measurement of Sulphadimidine is a document available to read on EtoBox.
1) The document describes an experiment to determine the pKa value of Sulphadimidine using spectroscopy. Buffers of varying pH were prepared and the absorbance of Sulphadimidine in each buffer was measured. 2) Based on the absorbance readings at different pH levels, the pKa of Sulphadimidine was calculated to be 7.66. This indicates it is a weak base. 3) The results show Sulphadimidine has low ionization at pH 7.4, with only 35.58% ionization. Increasing its ionization could improve the drug
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