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Can I read Functional and molecular features of the Id4^+^ germline stem cell population in mouse testes on EtoBox?
Functional and molecular features of the Id4^+^ germline stem cell population in mouse testes by Frieda Chan; Melissa J. Oatley; Amy V. Kaucher; Qi-En Yang; Charles J. Bieberich; Cooduvalli S. Shashikant; Jon M. Oatley is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Functional and molecular features of the Id4^+^ germline stem cell population in mouse testes about?
Chan et al. generated transgenic mice in which spermatogonial stem cells expressed an Id4-Gfp transgene. Id4-Gfp^+^ cells exist primarily as a subset of the type A~single~ pool and eventually comprise ∼2% of the undifferentiated spermatogonial population in adulthood. RNA sequencing analysis revealed genes whose expression is unique for the Id4-Gfp^+^/stem cell and Id4-Gfp^−^/progenitor fractions. These findings provide evidence that stem cells exist as a rare subset of the A~single~ pool and reveal transcriptome features distinguishing stem cell and progenitor states within the mammalian male germline.
Who reads Functional and molecular features of the Id4^+^ germline stem cell population in mouse testes?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Frieda Chan; Melissa J. Oatley; Amy V. Kaucher; Qi-En Yang; Charles J. Bieberich; Cooduvalli S. Shashikant; Jon M. Oatley
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2014
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)