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The salivary alpha-amylase concentration in patients with rheumatoid arthritis: A case–control study by Fahimeh Pakravan; Mehdi Nasr Isfahani; Mateen Ghorbani; Naghmeh Salesi; Mansour Salesi is a scholarly article available to read on EtoBox.

What is The salivary alpha-amylase concentration in patients with rheumatoid arthritis: A case–control study about?

## Background: Rheumatoid arthritis (RA) is one of the most common chronic inflammatory diseases. Previous studies have reported an association between stress and salivary alpha-amylase. The aim of this study was to investigate the concentration of salivary alpha-amylase in patients with RA (by elimination of stress factor). ## Materials and Methods: In this case–control study, we enrolled 50 patients with RA and 48 healthy patients as the control group. The perceived stress scale questionnaire was used to evaluate scores of stress in both case and control groups, and then the participants with high scores of stress were excluded from the study. Moreover, the alpha-amylase activity kit was used for the assessment of the levels of salivary alpha-amylase. In all analyses, the significance level was considered to be < 0.05. Finally, the obtained data were analyzed by SPSS22. ## Results: Our results indicated a high score of stress in the case group (19.42 ± 5.83 units) compared with the control group (18.02 ± 6.07 units) which was not statistically significant (__P__ < 0.248). Moreover, we demonstrated a high salivary alpha-amylase concentration in the case group (340.65 ± 38.04 units

Author

Fahimeh Pakravan; Mehdi Nasr Isfahani; Mateen Ghorbani; Naghmeh Salesi; Mansour Salesi

Published

2023