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Can I read Synthesis and Antifungal Activity of Novel Triazole Compounds Containing Piperazine Moiety on EtoBox?

Synthesis and Antifungal Activity of Novel Triazole Compounds Containing Piperazine Moiety by Yanwei Wang; Kehan Xu; Guojing Bai; Lei Huang; Qiuye Wu; Weihua Pan; Shichong Yu is a Chemistry article available to read on EtoBox.

What is Synthesis and Antifungal Activity of Novel Triazole Compounds Containing Piperazine Moiety about?

Design and synthesis of triazole library antifungal agents having piperazine side chains, analogues to fluconazole were documented. The synthesis highlighted utilization of the click chemistry on the basis of the active site of the cytochrome P450 14α-demethylase (CYP51). Their structures were characterized by 1 H-NMR, 13 C-NMR, MS and IR. The influences of piperazine moiety on in vitro antifungal activities of all the target compounds were evaluated against eight human pathogenic fungi.

Who reads Synthesis and Antifungal Activity of Novel Triazole Compounds Containing Piperazine Moiety?

It is typically read by researchers, students, and practitioners in Chemistry.

Author
Yanwei Wang; Kehan Xu; Guojing Bai; Lei Huang; Qiuye Wu; Weihua Pan; Shichong Yu
Publisher
MDPI AG
Published
2014
Language
EN
Field
Chemistry (Life Sciences)

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